Mycobacterium cookii

Mycobacterium cookii

Contents 1 Description 2 Pathogenesis 3 Type strain 4 References

Description

Gram-positive, nonmotile and polymorphic acid-fast rods (0.8 µm x 1.4–1.9 µm). Forms clumps, but not cords or cross bands. Does not form spores, capsules and aerial hyphae.

Colony characteristics

• Colonies are smooth and glistening with yellow-orange pigmentation (0.5–1.0 mm diameter, scotochromogenic).

Physiology

• Slow growth on Löwenstein-Jensen medium or Middlebrook 7H10 agar at 31°C (optimal temperature). No growth at 37°C, 42°C or 45°C.
• Most of the strains are susceptible to ethambutol, isoniazid, streptomycin, and rifampin.

Differential characteristics

• Phylogenetic position between the slowly growing pathogenic species and the saprotrophic rapidly growing species by partial 16S rDNA sequencing.

Pathogenesis

• Not pathogenic for humans, mice, guinea pigs and rabbits. Biosafety level 1.
• Provokes a non-specific hypersensitivity reaction to bovine tuberculin.

Type strain

Strain NZ2 = ATCC 49103 = CIP 105396 = DSM 43922 = JCM 12404.

References

• Kazda et al. 1990. Mycobacterium cookii sp. nov. Int. J. Syst. Bacteriol.,40, 217-223.

Mycobacteria (including Nontuberculous) Slowly growing (R1P=photochromogenic; R2S=scotochromogenic; R3N=nonchromogenic) Long helix 18 (TKHGC) M. tuberculosis group MTC: M. tuberculosis · M. bovis · M. africanum · M. microti · M. canetti • M. caprae • M. pinnipedii MPM: R1P (M. marinum) • R2S (M. pseudoshottsii) • R3N (M. ulcerans, M. shottsii, M. liflandii) Leprosy: M. leprae • M. lepraemurium • M. lepromatosis R3N: other (M. lacus, M. kumamotonense) K/H groups M. kansasii group MAC: R3N (M. intracellulare/M. avium, M. avium subspecies paratuberculosis, M. chimaera) • R2S (M. bohemicum) GK: R1P (M. kansasii) • R3N (M. gastri) R2S (M. nebraskense, M. seoulense) • R3N (M. scrofulaceum) M. haemophilum group M. haemophilum • R2S (M. szulgai) • R3N ( M. malmoense) M. gordonae group R1P (M. asiaticum) • R2S (M. gordonae) M. conspicuum group R2S (M. conspicuum) Long helix 18 (other) M. xenopi group M. botniense • M. shimoidei/M. xenopi • M. heckeshornense • M. hassiacum M. celatum group R2S (M. cookii) • R3N (M. branderi, M. celatum) M. hiberniae group M. terrae • M. hiberniae • M. nonchromogenicum/M. arupense Short helix 18 M. simiae clade M. simiae group: R3N (M. genavense/M. triplex, M. florentinum/M. montefiorense, M. heidelbergense/M. parmense, M. simiae) • R2S (M. lentiflavum) M. kubicae group: R3N (M. parascrofulaceum) • R2S (M. palustre/M. kubicae) M. interjectum group: M. interjectum • M. saskatchewanense M. intermedium group M. intermedium Ungrouped M. triviale • M. doricum • M. tusciae • M. arosiense Rapidly growing/ Runyon IV M. neoaurum group M. mageritense • M. wolinskyi M. canariasense • M. cosmeticum • M. diernhoferi • M. hodleri • M. frederiksbergense • M. neoaurum M. brisbanense M. fluoroanthenivorans F/T groups M. fortuitum group M. chitae/M. fallax/M. gadium M. rhodesiae • M. houstonense M. neworleansense/M. boenickei/M. fortuitum/M. porcinum/M. senegalense M. septicum/M. peregrinum/M. alvei M. farcinogenes M. vaccae group M. obuense/M. gilvum/M. parafortuitum M. chlorophenolicum/M. chubuense • M. psychrotolerans/M. sphagni • M. aubagnense/M. mucogenicum/M. phocaicum AV (M. aurum, M. vanbaalenii, M. vaccae) • M. austroafricanum • M. pyrenivorans M. poriferae M. smegmatis group M. agri/M. thermoresistibile · M. duvalii/M. flavescens • M. monacense • M. pulveris/M. conceptionense/M. moriokaense M. novocastrense/M. brumae/M. phlei M. confluentis/M. madagascariense M. smegmatis/M. goodii M. chelonae group M. komossense • M. murale/M. tokaiense • M. aichiense • M. chelonae • M. abscessus • M. immunogenum • M. massiliense • M. bolletii M. elephantis group M. elephantis • M. holsaticum